2019-07-02

It is notable that CTSS is a differentially expressed gene in the kidney of IgAN patients and associated with the pathogenesis of IgAN (31, 32). In this study, we found significantly up-regulated CTSS expression in the kidney tissues, particularly in the glomerular mesangium and tubular epithelial cells from human IgAN patients, and higher

Functional Associations CTSS has 5,430 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 78 datasets. Ctss Gene Detail Summary Symbol. Ctss Name. cathepsin S. Synonyms. Cat S Feature Type.

Ctss gene

Assay details for Ctss, CPTAC-3897. Official Gene Symbol, Other Aliases. Ctss, Cats Official Gene Symbol: Ctss; Peptide Sequence: YIQLPFGDEDALK Apr 28, 2018 data at three levels: CTSS-, cluster- and gene-level (Fig.1A), described below. CAGEfightR provides efficient functions for importing multiple The expression levels of four genes identified by microarray screening (PLCB2, HVCN1, CTSS, and DEF8) and one purine/thiopurine related gene (NME6) HLA-DRB1 * Gene and some genes involved in inflammation and immunity (IL-7R, GPC5, CTSS) have been linked to risk of MS and the response to treatment Läs mer om Anti-CTSS Rabbit polyclonal antibody.

2020-04-09 · Moreover, Gene Set Enrichment Analysis (GSEA) was also employed, which indicated that LRFI chickens increased expression of genes related to mitochondrial function. Furthermore, protein network interaction and function analyses revealed ND2, ND4, CYTB, RAC2, VCAM1, CTSS and TLR4 were key genes for feed efficiency.

In addition to its role in antigen processing, Ctss can remodel the ECM in … 2011-04-01 Plasmid pLEX307-CTSS-G418 from Dr. Alejandro Chavez's lab contains the insert CTSS and is published in Unpublished This plasmid is available through Addgene. Cathepsin S (CTSS) activity is increased in tears of Sjögren’s syndrome (SS) patients.

Sequence variants and/or copy number variants (deletions/duplications) within the CTSS gene will be detected with >99% sensitivity. Variants classified as unknown significance (VUS), likely pathogenic, or pathogenic will be reported.

Because this designation had been used for a different gene (see 600550), the official name of the gene identified by Shi et al. (1995) became cathepsin K. The cathepsin K cDNA produces a single 1.7-kb transcript as detected on Northern blots of 15-day-old monocyte-derived macrophage RNA, but was not expressed in human monocytes or alveolar macrophages. Gene: Ctss ENSMUSG00000038642 Gene Synonyms. Cat S. Location This gene has proteins that correspond to the following Uniprot identifiers: P30279.

It is notable that CTSS is a differentially expressed gene in the kidney of IgAN patients and associated with the pathogenesis of IgAN (31, 32).
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Cytochrome P450 Gene-gene interplay and gene-diet interactions involving the MTNR1B.

Diseases associated with CTSS include Dacryoadenitis Jan 15, 2021 3.7 CTSS clustering. Transcription start sites are found in the promoter region of a gene and reflect the transcriptional activity of that promoter ( Apr 15, 2015 Produced from its cognate CTSS gene on chromosome 1q21, human cathepsin S is synthesized as a pre-proenzyme of 331 amino acids in Gene symbol, CTSS.
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Phenotype data for mouse gene Ctss. Discover Ctss's significant phenotypes, expression, images, histopathology and more. Data for gene Ctss is all freely available for download.

Catalog # A15629, A15630 Non-tailed | Desalted | Pair : See in cart, See in cart Add Pair To Cart Add to Array View Description: Homo sapiens cathepsin S (CTSS), transcript variant 1, mRNA. (from RefSeq NM_004079) RefSeq Summary (NM_004079): The preproprotein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that participates in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. . The mature protein cleaves the invariant CTSS (cathepsin S), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol. Atlas of Genetics and Cytogenetics in Oncology and Haematology Home Genes Leukemias Solid Tumors Cancer-Prone Deep Insight Case Reports Journals Portal Teaching Gene Name: Homo sapiens cathepsin S (CTSS), transcript variant 1: Database Link: Entrez Gene 1520 Human. Background: CTSS (Cathepsin S) is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia.